Cancer cervix accounts for 80% of female genital cancer and is the most common cancer. India 27% incidence all over world. The mortality due to 14.7%. To assess reliability downstaging in early detection precancerous lesion. correlate findings 110 women with unhealthy by cytology, colposcopy directed biopsies. work was carried out continuously one year 2 months. were evaluated. When Cytology co...

Background an objective: Renal transplantation may be considered as the only effective long-term therapy for chronic renal failure. Better surgical techniques and recent advances in immunosuppressive therapy allows patients to survive for many years. However, cutaneous lesions (Cosmetic, infectious, pre-cancerous and neoplastic) can be a significant problem for this group of patients. This stud...

Increased expression of Bcl-2 protein has been demonstrated in various cancerous and precancerous lesions. The B-cell lymphoma-2 gene is a proto-oncogene that inhibits apoptosis, therefore keeping the cell alive. Mutations leads to an overexpression products leading apoptosis impairment resulting neoplastic changes as consequence. Hence, objective study was investigate fibro epithelial polyp (F...

  leukoplakia,erythroplakia and palatal changes due to reversed smoking(R.S) are considered as precancerous lesions .oral lichen planus has been considered as a precancerous condition.to evaluate  precancerous lesions in factory workers of Kerman city,a cross sectional study was designed in which 1167 workers(1070 men,97 women,mean age=31.8) were participated.dental mirrors,explorers and flas...

background and aims. several diagnostic methods are being employed to detect benign and malignant lesions, one of which is silver nitrate staining for organizer regions. the number of nucleolar organizing regions (nors) can be used to show the degree of cell activity or metabolism in pathologic lesions. this study was designed to evaluate nors as determinants of precancerous and squamous cell c...

Background: Precancerous lesions are disorders that are highlylikely to become malignant. Early diagnosis of precancerous skinlesions helps to prevent skin cancers. The aim of this study wasclinicopathological assessment of precancerous skin lesions inpatients referred to the dermatology department of Imam Rezahospital.Method: Two hundred and nine patients who were diagnosed withprecancerous le...

PURPOSE It is important to identify the definitive molecular switches involved in the malignant transformation of premalignant tissues. Cellular senescence is a specific characteristic of precancerous tissues, but not of cancers, which might reflect tumorigenesis-protecting mechanisms in premalignant lesions. Polycomb protein Bmi1, which is a potent negative regulator of the p16INK4 gene, suppr...

Pseudo-tumoral lesions of the cervix implies some reactive, non-neoplastic changes (metaplasia, hyperplasia, inflammation) that, occasionally, are wrong interpreted as precancerous or malign lesions. Even some can present architectural or cytological abnormal aspects, these are different from the one noted in carcinomas or the precursor lesions of carcinomas. Them recognition is indispensable i...